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A Role for Copper in the Toxicity of Zinc-Deficient Superoxide Dismutase to Motor Neurons in Amyotrophic Lateral Sclerosis

In the 16 years since mutations to copper, zinc superoxide dismutase (SOD1) were first linked to familial amyotrophic lateral sclerosis (ALS), a multitude of apparently contradictory results have prevented any general consensus to emerge about the mechanism of toxicity. A decade ago, we showed that...

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Bibliografiske detaljer
Main Authors: Trumbull, Kari A., Beckman, Joseph S.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842582/
https://ncbi.nlm.nih.gov/pubmed/19309264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2574
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