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Rotational dynamics of DNA on the nucleosome surface markedly impact accessibility to a DNA repair enzyme
Histones play a crucial role in the organization of DNA in the nucleus, but their presence can prevent interactions with DNA binding proteins responsible for repair of DNA damage. Uracil is an abundant mutagenic lesion recognized by uracil DNA glycosylase (UDG) in the first step of base excision rep...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842065/ https://ncbi.nlm.nih.gov/pubmed/20176960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914443107 |
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