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Accessing DNA Damage in Chromatin: Preparing the Chromatin Landscape for Base Excision Repair

DNA damage in chromatin comes in many forms, including single base lesions that induce base excision repair (BER). We (and others) have shown that the structural location of DNA lesions within nucleosomes greatly influences their accessibility to repair enzymes. Indeed, a difference in the location...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Rodriguez, Yesenia, Hinz, John M., Smerdon, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522338/
https://ncbi.nlm.nih.gov/pubmed/25957487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.021
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