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Accessing DNA Damage in Chromatin: Preparing the Chromatin Landscape for Base Excision Repair
DNA damage in chromatin comes in many forms, including single base lesions that induce base excision repair (BER). We (and others) have shown that the structural location of DNA lesions within nucleosomes greatly influences their accessibility to repair enzymes. Indeed, a difference in the location...
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Publicado no: | DNA Repair (Amst) |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4522338/ https://ncbi.nlm.nih.gov/pubmed/25957487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.021 |
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