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Accessing DNA Damage in Chromatin: Preparing the Chromatin Landscape for Base Excision Repair

DNA damage in chromatin comes in many forms, including single base lesions that induce base excision repair (BER). We (and others) have shown that the structural location of DNA lesions within nucleosomes greatly influences their accessibility to repair enzymes. Indeed, a difference in the location...

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Detalles Bibliográficos
Publicado en:DNA Repair (Amst)
Autores principales: Rodriguez, Yesenia, Hinz, John M., Smerdon, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4522338/
https://ncbi.nlm.nih.gov/pubmed/25957487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.021
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