Cutting Edge: Roles of Toll-Like Receptor 4 and IL-23 in IL-17 Expression in Response to Klebsiella pneumoniae Infection

Local production of IL-17 is a significant factor in effective host defense against Gram-negative bacteria. However, the proximal events mediating IL-17 elaboration by T cells remain unclear. In this study, we show in vivo that intact Toll-like receptor 4 signaling in the lung is required for induct...

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Autors principals: Happel, Kyle I., Zheng, Mingquan, Young, Erana, Quinton, Lee J., Lockhart, Euan, Ramsay, Alistair J., Shellito, Judd E., Schurr, Jill R., Bagby, Gregory J., Nelson, Steve, Kolls, Jay K.
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841978/
https://ncbi.nlm.nih.gov/pubmed/12707317
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