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Increased Host Resistance against Pneumocystis carinii Pneumonia in γδ T-Cell-Deficient Mice: Protective Role of Gamma Interferon and CD8(+) T Cells

Although a clear relationship between αβ T-cell receptor-positive (αβ-TCR(+)) CD4(+) T cells and susceptibility to Pneumocystis carinii infection exists, the role of other T-cell subsets is less clearly defined. Previous studies have shown that γδ-TCR(+) T cells infiltrate into the lung during P. ca...

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Main Authors: Steele, Chad, Zheng, Mingquan, Young, Erana, Marrero, Luis, Shellito, Judd E., Kolls, Jay K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC128275/
https://ncbi.nlm.nih.gov/pubmed/12183572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.5208-5215.2002
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