Reduction in intensity of Pneumocystis carinii pneumonia in mice by aerosol administration of gamma interferon.

Pneumocystis carinii pneumonia in patients with AIDS may result from impaired local release of gamma interferon from lung lymphocytes and subsequent failure of macrophage activation. We tested this hypothesis with mice rendered immunodeficient by selective depletion of CD4+ lymphocytes and inoculate...

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Bibliographic Details
Main Authors: Beck, J M, Liggitt, H D, Brunette, E N, Fuchs, H J, Shellito, J E, Debs, R J
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC258968/
https://ncbi.nlm.nih.gov/pubmed/1682252
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