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Novel pentamidine analogs in the treatment of experimental Pneumocystis carinii pneumonia.

We have recently demonstrated that substitution of imidazoline moieties for the amidine groups of pentamidine produces a molecule that is effective against rat Pneumocystis carinii pneumonia and that is apparently less toxic than pentamidine. For this reason, 10 novel imidazoline substituted compoun...

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Main Authors: Jones, S K, Hall, J E, Allen, M A, Morrison, S D, Ohemeng, K A, Reddy, V V, Geratz, J D, Tidwell, R R
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC171751/
https://ncbi.nlm.nih.gov/pubmed/2393262
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