Novel pentamidine analogs in the treatment of experimental Pneumocystis carinii pneumonia.

We have recently demonstrated that substitution of imidazoline moieties for the amidine groups of pentamidine produces a molecule that is effective against rat Pneumocystis carinii pneumonia and that is apparently less toxic than pentamidine. For this reason, 10 novel imidazoline substituted compoun...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Jones, S K, Hall, J E, Allen, M A, Morrison, S D, Ohemeng, K A, Reddy, V V, Geratz, J D, Tidwell, R R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2393262/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1026
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