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Central Role of Toll-Like Receptor 4 Signaling and Host Defense in Experimental Pneumonia Caused by Gram-Negative Bacteria

Toll-like receptor 4 (TLR4) has been identified as a receptor for lipopolysaccharide. However, the precise role of TLR4 in regulating gene expression in response to an infection caused by gram-negative bacteria has not been fully elucidated. The role of TLR4 signaling in coordinating gene expression...

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Detalhes bibliográficos
Main Authors: Schurr, Jill R., Young, Erana, Byrne, Pat, Steele, Chad, Shellito, Judd E., Kolls, Jay K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538991/
https://ncbi.nlm.nih.gov/pubmed/15618193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.532-545.2005
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