Role of Toll-Like Receptor 4 in Gram-Positive and Gram-Negative Pneumonia in Mice

To determine the role of Toll-like receptor 4 (TLR4) in the immune response to pneumonia, C3H/HeJ mice (which display a mutant nonfunctional TLR4) and C3H/HeN wild-type mice were intranasally infected with either Streptococcus pneumoniae (a common gram-positive respiratory pathogen) or Klebsiella pn...

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Detalhes bibliográficos
Principais autores: Branger, Judith, Knapp, Sylvia, Weijer, Sebastiaan, Leemans, Jaklien C., Pater, Jennie M., Speelman, Peter, Florquin, Sandrine, van der Poll, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321591/
https://ncbi.nlm.nih.gov/pubmed/14742522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.788-794.2004
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