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Role of Toll-Like Receptor 4 in Gram-Positive and Gram-Negative Pneumonia in Mice

To determine the role of Toll-like receptor 4 (TLR4) in the immune response to pneumonia, C3H/HeJ mice (which display a mutant nonfunctional TLR4) and C3H/HeN wild-type mice were intranasally infected with either Streptococcus pneumoniae (a common gram-positive respiratory pathogen) or Klebsiella pn...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:Infect Immun
Hauptverfasser: Branger, Judith, Knapp, Sylvia, Weijer, Sebastiaan, Leemans, Jaklien C., Pater, Jennie M., Speelman, Peter, Florquin, Sandrine, van der Poll, Tom
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2004
Schlagworte:
Host Response and Inflammation
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321591/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742522/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.2.788-794.2004
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