Interleukin-10 Negatively Regulates Local Cytokine and Chemokine Production but Does Not Influence Antibacterial Host Defense during Murine Pneumococcal Meningitis

To determine the role of endogenous interleukin-10 (IL-10) in local host defense during pneumococcal meningitis, the inflammatory responses of IL-10-gene-deficient and wild-type mice after the induction of meningitis were compared. The absence of IL-10 was associated with higher cytokine and chemoki...

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Detalhes bibliográficos
Main Authors: Zwijnenburg, Petra J. G., van der Poll, Tom, Florquin, Sandrine, Roord, John J., van Furth, A. Marceline
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152042/
https://ncbi.nlm.nih.gov/pubmed/12654856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.2276-2279.2003
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