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SIRT3 regulates fatty acid oxidation via reversible enzyme deacetylation
Sirtuins are NAD(+)-dependent protein deacetylases and mediate adaptive responses to a variety of stresses, including calorie restriction and metabolic stress. Sirtuin 3 (SIRT3) is localized in the mitochondrial matrix where it regulates the acetylation levels of metabolic enzymes, including acetyl...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841477/ https://ncbi.nlm.nih.gov/pubmed/20203611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08778 |
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