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Mechanisms underlying erythrocyte and endothelial nitrite reduction to NO in hypoxia: role for Xanthine Oxidoreductase and eNOS

Reduction of nitrite (NO(2)(−)) provides a major source of nitric oxide (NO) in the circulation, especially in hypoxemic conditions. Our previous studies suggest that xanthine oxidoreductase (XOR) is an important nitrite reductase in the heart and kidney. Herein, we have demonstrated that conversion...

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Hlavní autoři: Webb, Andrew J., Milsom, Alexandra B., Rathod, Krishnaraj S., Chu, Wai Lum, Qureshi, Shehla, Lovell, Matthew J., Lecomte, Florence M.J., Perrett, David, Raimondo, Carmello, Khoshbin, Espeed, Ahmed, Zubair, Uppal, Rakesh, Benjamin, Nigel, Hobbs, Adrian J., Ahluwalia, Amrita
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841343/
https://ncbi.nlm.nih.gov/pubmed/18818408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.175810
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