Mechanisms underlying erythrocyte and endothelial nitrite reduction to NO in hypoxia: role for Xanthine Oxidoreductase and eNOS

Reduction of nitrite (NO(2)(−)) provides a major source of nitric oxide (NO) in the circulation, especially in hypoxemic conditions. Our previous studies suggest that xanthine oxidoreductase (XOR) is an important nitrite reductase in the heart and kidney. Herein, we have demonstrated that conversion...

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Detalhes bibliográficos
Main Authors: Webb, Andrew J., Milsom, Alexandra B., Rathod, Krishnaraj S., Chu, Wai Lum, Qureshi, Shehla, Lovell, Matthew J., Lecomte, Florence M.J., Perrett, David, Raimondo, Carmello, Khoshbin, Espeed, Ahmed, Zubair, Uppal, Rakesh, Benjamin, Nigel, Hobbs, Adrian J., Ahluwalia, Amrita
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841343/
https://ncbi.nlm.nih.gov/pubmed/18818408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.175810
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