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Mechanisms underlying erythrocyte and endothelial nitrite reduction to NO in hypoxia: role for Xanthine Oxidoreductase and eNOS

Reduction of nitrite (NO(2)(−)) provides a major source of nitric oxide (NO) in the circulation, especially in hypoxemic conditions. Our previous studies suggest that xanthine oxidoreductase (XOR) is an important nitrite reductase in the heart and kidney. Herein, we have demonstrated that conversion...

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Détails bibliographiques
Auteurs principaux: Webb, Andrew J., Milsom, Alexandra B., Rathod, Krishnaraj S., Chu, Wai Lum, Qureshi, Shehla, Lovell, Matthew J., Lecomte, Florence M.J., Perrett, David, Raimondo, Carmello, Khoshbin, Espeed, Ahmed, Zubair, Uppal, Rakesh, Benjamin, Nigel, Hobbs, Adrian J., Ahluwalia, Amrita
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841343/
https://ncbi.nlm.nih.gov/pubmed/18818408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.175810
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