Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase

BACKGROUND: Pulmonary hypertension (PH) is a multi-factorial disease characterized by increased pulmonary vascular resistance and right ventricular failure; morbidity and mortality remain unacceptably high. Loss of nitric oxide (NO) bioactivity is thought to contribute to the pathogenesis of PH and...

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Hauptverfasser: Baliga, Reshma S, Milsom, Alexandra B, Ghosh, Suborno M, Trinder, Sarah L, MacAllister, Raymond J, Ahluwalia, Amrita, Hobbs, Adrian J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502837/
https://ncbi.nlm.nih.gov/pubmed/22572914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.100586
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