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Widespread and tissue specific age-related DNA methylation changes in mice
Aberrant methylation of promoter CpG islands in cancer is associated with silencing of tumor-suppressor genes, and age-dependent hypermethylation in normal appearing mucosa may be a risk factor for human colon cancer. It is not known whether this age-related DNA methylation phenomenon is specific to...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840983/ https://ncbi.nlm.nih.gov/pubmed/20107151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.096826.109 |
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