Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease

BACKGROUND: The inflammatory disorders type 1 diabetes (T1D) and celiac disease co-segregate in populations, suggesting a common genetic origin. Both are associated with the HLA class II genes on chromosome 6p21, and the present paper tested whether non-HLA loci are shared. METHODS: We evaluated eig...

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Detalhes bibliográficos
Main Authors: Smyth, Deborah J, Plagnol, Vincent, Walker, Neil M, Cooper, Jason D, Downes, Kate, Yang, Jennie HM, Howson, Joanna MM, Stevens, Helen, McManus, Ross, Wijmenga, Cisca, Heap, Graham A., Dubois, Patrick C., Clayton, David G., Hunt, Karen A, van Heel, David A, Todd, John A
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840835/
https://ncbi.nlm.nih.gov/pubmed/19073967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0807917
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