Dicer Inactivation in Osteoprogenitor Cells Compromises Fetal Survival and Bone Formation, While Excision in Differentiated Osteoblasts Increases Bone Mass in the Adult Mouse

MicroRNA attenuation of protein translation has emerged as an important regulator of mesenchymal cell differentiation into the osteoblast lineage. A compelling question is the extent to which miR biogenesis is obligatory for bone formation. Here we show conditional deletion of Dicer in osteoprogenit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gaur, Tripti, Hussain, Sadiq, Mudhasani, Rajini, Parulkar, Isha, Colby, Jennifer L., Frederick, Dana, Kream, Barbara E., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S., Jones, Stephen N., Lian, Jane B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840721/
https://ncbi.nlm.nih.gov/pubmed/20079730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.01.008
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