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Bone marrow osteoprogenitors are depleted whereas osteoblasts are expanded independent of the osteogenic vasculature in response to zoledronic acid

Zoledronic acid (ZOL) is an antiresorptive drug used to prevent bone loss in a variety of conditions, acting mainly through suppression of osteoclast activity. There is growing evidence that ZOL can also affect cells of the mesenchymal lineage in bone. We present novel data revealing significant cha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:FASEB J
Päätekijät: Hughes, Russell, Chen, Xinyue, Hunter, Keith D., Hobbs, Jamie K., Holen, Ingunn, Brown, Nicola J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Federation of American Societies for Experimental Biology 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902700/
https://ncbi.nlm.nih.gov/pubmed/31490705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900553RR
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