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NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90
The type I lissencephaly gene product LIS1, a key regulator of cytoplasmic dynein, is critical for cell proliferation, survival, and neuronal migration. However, little is known about the regulation of LIS1. Here, we identify a previously uncharacterized mammalian homolog of Aspergillus NudC, NudCL2...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840461/ https://ncbi.nlm.nih.gov/pubmed/20133715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914307107 |
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