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The Adaptor Molecule MyD88 Activates PI-3 Kinase Signaling in CD4(+) T Cells and Enables CpG Oligodeoxynucleotide-Mediated Costimulation
While T cells respond directly to toll-like receptor (TLR) agonists, TLR-signaling pathways in T cells are poorly characterized. Here we demonstrate in CD4(+) T cells that CpG DNA directly enhances proliferation, prevents anergy, and augments humoral responses to a T cell-dependent antigen by a Myel...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840381/ https://ncbi.nlm.nih.gov/pubmed/17055754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2006.08.023 |
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