Premature replacement of μ with α immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation

Sequentially along B cell differentiation, the different classes of membrane Ig heavy chains associate with the Igα/Igβ heterodimer within the B cell receptor (BCR). Whether each Ig class conveys specific signals adapted to the corresponding differentiation stage remains debated. We investigated the...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Duchez, Sophie, Amin, Rada, Cogné, Nadine, Delpy, Laurent, Sirac, Christophe, Pascal, Virginie, Corthésy, Blaise, Cogné, Michel
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840347/
https://ncbi.nlm.nih.gov/pubmed/20133609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912393107
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky