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Conformation-dependent Formation of the G[8-5]U Intrastrand Cross-link in 5-Bromouracil-containing G-quadruplex DNA Induced by UVA Irradiation
G-quadruplex motifs are known to be present in telomeres of human and other organisms. Recent bioinformatic studies also revealed the widespread existence of these motifs in promoter regions of human genes. Treatment of cultured cells with 5-bromo-2’-deoxyuridine ((Br)dU) is known to result in the s...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840199/ https://ncbi.nlm.nih.gov/pubmed/20166754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901861w |
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