Simultaneous Visualization of Pro-tumorigenic Src and MT1-MMP Activities with Fluorescence Resonance Energy Transfer

Both Src kinase and membrane type 1 matrix metalloproteinase (MT1-MMP) play critical roles in cancer invasion and metastasis. It is not clear, however, how the spatiotemporal activation of these two critical enzymes is coordinated in response to an oncogenic epithelial growth factor (EGF) stimulatio...

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Detalhes bibliográficos
Main Authors: Ouyang, Mingxing, Huang, He, Shaner, Nathan, Remacle, Albert G., Shiryaev, Sergey A, Strongin, Alex Y., Tsien, Roger Y., Wang, Yingxiao
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840183/
https://ncbi.nlm.nih.gov/pubmed/20197470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3698
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