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Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

High-resolution imaging of molecules intrinsically involved in malignancy and metastasis would be of great value for clinical detection and staging of tumors. We now report in vivo visualization of matrix metalloproteinase activities by MRI and fluorescence of dendrimeric nanoparticles coated with a...

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Autori principali: Olson, Emilia S., Jiang, Tao, Aguilera, Todd A., Nguyen, Quyen T., Ellies, Lesley G., Scadeng, Miriam, Tsien, Roger Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840175/
https://ncbi.nlm.nih.gov/pubmed/20160077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910283107
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