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Ketosteroid isomerase provides further support for the idea that enzymes work by electrostatic preorganization
One of the best systems for exploring the origin of enzyme catalysis has been the reaction of ketosteroid isomerase (KSI). Studies of the binding of phenolates to KSI have been taken as proof that the electrostatic preorganization effect only makes a minor contribution to the binding of the real, mu...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840163/ https://ncbi.nlm.nih.gov/pubmed/20150513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914579107 |
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