Diacylglycerol kinase α mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI

Diacylglycerol kinases (DGKs) convert diacylglycerol (DAG) into phosphatidic acid (PA), acting as molecular switches between DAG- and PA-mediated signaling. We previously showed that Src-dependent activation and plasma membrane recruitment of DGKα are required for growth-factor-induced cell migratio...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Chianale, Federica, Rainero, Elena, Cianflone, Cristina, Bettio, Valentina, Pighini, Andrea, Porporato, Paolo E., Filigheddu, Nicoletta, Serini, Guido, Sinigaglia, Fabiola, Baldanzi, Gianluca, Graziani, Andrea
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840123/
https://ncbi.nlm.nih.gov/pubmed/20160093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908326107
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares