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Anti-CD22 Immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22 Positive Hematologic Malignancies of Childhood: Pre-clinical Studies and Phase I Clinical Trial

PURPOSE: Although most children with B-lineage acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL) are cured, new agents are needed to overcome drug resistance and reduce toxicities of chemotherapy. We hypothesized that the novel anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22, CAT-3888) w...

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Bibliografische gegevens
Hoofdauteurs: Wayne, Alan S., Kreitman, Robert J., Findley, Harry W., Lew, Glen, Delbrook, Cynthia, Steinberg, Seth M., Stetler-Stevenson, Maryalice, FitzGerald, David J., Pastan, Ira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840067/
https://ncbi.nlm.nih.gov/pubmed/20215554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2980
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