Cytotoxicity of the anti-CD22 immunotoxin HA22 (CAT-8015) against paediatric acute lymphoblastic leukaemia

Acute lymphoblastic leukaemia (ALL) remains the most frequent cause of cancer-related mortality in paediatrics and outcome is poor for patients who have high-risk ALL or relapse. HA22 (CAT-8015) is an immunotoxin composed of an anti-CD22 variable fragment linked to a 38 kDa truncated protein derived...

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Udgivet i:Br J Haematol
Main Authors: Mussai, Francis, Campana, Dario, Bhojwani, Deepa, Stetler-Stevenson, Maryalice, Steinberg, Seth M., Wayne, Alan S., Pastan, Ira
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316383/
https://ncbi.nlm.nih.gov/pubmed/20528877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2010.08251.x
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