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Phase II Trial of Recombinant Immunotoxin RFB4(dsFv)-PE38 (BL22) in Patients With Hairy Cell Leukemia

PURPOSE: To conduct a phase II trial in chemoresistant hairy cell leukemia (HCL) with BL22, a recombinant anti-CD22 immunotoxin which showed phase I activity in HCL. PATIENTS AND METHODS: Eligible patients had relapsed/refractory HCL and needed treatment based on blood counts. Patients were stratifi...

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Detalhes bibliográficos
Main Authors: Kreitman, Robert J., Stetler-Stevenson, Maryalice, Margulies, Inger, Noel, Pierre, FitzGerald, David J.P., Wilson, Wyndham H., Pastan, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702232/
https://ncbi.nlm.nih.gov/pubmed/19414673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.20.2630
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