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Mechanisms Underlying Blockade of Allograft Acceptance by TLR Ligands

Immune activation via TLRs is known to prevent transplantation tolerance in multiple animal models. To investigate the mechanisms underlying this barrier to tolerance induction, we used complementary murine models of skin and cardiac transplantation in which prolonged allograft acceptance is either...

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Bibliografiske detaljer
Main Authors: Porrett, Paige M., Yuan, Xueli, LaRosa, David F., Walsh, Patrick T., Yang, Jaeseok, Gao, Wenda, Li, Peiying, Zhang, Jidong, Ansari, Javeed M., Hancock, Wayne W., Sayegh, Mohamed H., Koulmanda, Maria, Strom, Terry B., Turka, Laurence A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840047/
https://ncbi.nlm.nih.gov/pubmed/18641305
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