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Three step synthesis of single diastereoisomers of the vicinal trifluoro motif

A three step route to single diastereoisomers of the vicinal trifluoromethyl motif is described. The route starts from either syn- or anti-α,β-epoxy alcohols and takes a direct approach in that each of the three steps introduces a fluorine atom in a regio- and stereo-specific manner. Starting from e...

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Autori principali: Brunet, Vincent A, Slawin, Alexandra M Z, O'Hagan, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839549/
https://ncbi.nlm.nih.gov/pubmed/20300509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.5.61
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