RNAi-mediated CCR5 Silencing by LFA-1-targeted Nanoparticles Prevents HIV Infection in BLT Mice

RNA interference (RNAi)–mediated knockdown of gene expression offers a novel treatment strategy for human immunodeficiency virus (HIV) infection. However, the major hurdle for clinical use is a practical strategy for small interfering RNA (siRNA) delivery to the multiple immune cell types important...

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Autors principals: Kim, Sang-Soo, Peer, Dan, Kumar, Priti, Subramanya, Sandesh, Wu, Huaquan, Asthana, Deshratan, Habiro, Katsuyoshi, Yang, Yong-Guang, Manjunath, N, Shimaoka, Motomu, Shankar, Premlata
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839291/
https://ncbi.nlm.nih.gov/pubmed/19997090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.271
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