Deficiency of the Housekeeping Gene Hypoxanthine–Guanine Phosphoribosyltransferase (HPRT) Dysregulates Neurogenesis

Neuronal transcription factors play vital roles in the specification and development of neurons, including dopaminergic (DA) neurons. Mutations in the gene encoding the purine biosynthetic enzyme hypoxanthine–guanine phosphoribosyltransferase (HPRT) cause the resulting intractable and largely untrea...

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Bibliografische gegevens
Hoofdauteurs: Guibinga, Ghiabe-Henri, Hsu, Stephen, Friedmann, Theodore
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2009
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839227/
https://ncbi.nlm.nih.gov/pubmed/19672249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.178
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