In vitro and in vivo effects of the antimycotic drug ketoconazole on sterol synthesis.
Ketoconazole, an orally active antimycotic drug, is a potent inhibitor of ergosterol biosynthesis in Candida albicans when added to culture media which support yeast or mycelial growth or to cultures containing outgrown mycelium. This inhibition coincides with accumulation of sterols with a methyl g...
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| Published in: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1980
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6250469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.6.922 |
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