In vitro and in vivo effects of the antimycotic drug ketoconazole on sterol synthesis.

Ketoconazole, an orally active antimycotic drug, is a potent inhibitor of ergosterol biosynthesis in Candida albicans when added to culture media which support yeast or mycelial growth or to cultures containing outgrown mycelium. This inhibition coincides with accumulation of sterols with a methyl g...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Van den Bossche, H, Willemsens, G, Cools, W, Cornelissen, F, Lauwers, W F, van Cutsem, J M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1980
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6250469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.6.922
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