In vitro and in vivo effects of the antimycotic drug ketoconazole on sterol synthesis.

Ketoconazole, an orally active antimycotic drug, is a potent inhibitor of ergosterol biosynthesis in Candida albicans when added to culture media which support yeast or mycelial growth or to cultures containing outgrown mycelium. This inhibition coincides with accumulation of sterols with a methyl g...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Van den Bossche, H, Willemsens, G, Cools, W, Cornelissen, F, Lauwers, W F, van Cutsem, J M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1980
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6250469/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.6.922
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