A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry

BACKGROUND: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflows. The improved spectral quality enables more accurate de novo sequencing for identification of post-translational modif...

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Autori principali: Pan, Chongle, Park, Byung H, McDonald, William H, Carey, Patricia A, Banfield, Jillian F, VerBerkmoes, Nathan C, Hettich, Robert L, Samatova, Nagiza F
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838866/
https://ncbi.nlm.nih.gov/pubmed/20205730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-118
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