2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent.
A newly synthesized pyrimidine analog, 2'-fluoro-5-iodo-aracytosine (FIAC), suppressed by 90% the replication of various strains of herpes simplex virus types 1 and 2 at concentrations of 0.0025 to 0.0126 microM. Cytotoxicity was minimal, as determined by trypan blue dye exclusion with norman Vero,...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1980
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6249196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.5.803 |
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