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2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent.

A newly synthesized pyrimidine analog, 2'-fluoro-5-iodo-aracytosine (FIAC), suppressed by 90% the replication of various strains of herpes simplex virus types 1 and 2 at concentrations of 0.0025 to 0.0126 microM. Cytotoxicity was minimal, as determined by trypan blue dye exclusion with norman V...

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Bibliografische gegevens
Hoofdauteurs: Lopez, C, Watanabe, K A, Fox, J J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1980
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC283879/
https://ncbi.nlm.nih.gov/pubmed/6249196
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