2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent.

A newly synthesized pyrimidine analog, 2'-fluoro-5-iodo-aracytosine (FIAC), suppressed by 90% the replication of various strains of herpes simplex virus types 1 and 2 at concentrations of 0.0025 to 0.0126 microM. Cytotoxicity was minimal, as determined by trypan blue dye exclusion with norman Vero,...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Lopez, C, Watanabe, K A, Fox, J J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1980
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6249196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.5.803
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