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Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures

CFTR is a highly regulated apical chloride channel of epithelial cells that is mutated in cystic fibrosis (CF). In this study, we characterized the apical stability and intracellular trafficking of wild-type and mutant CFTR in its native environment, i.e., highly differentiated primary human airway...

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Autori principali: Cholon, Deborah M., O'Neal, Wanda K., Randell, Scott H., Riordan, John R., Gentzsch, Martina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838667/
https://ncbi.nlm.nih.gov/pubmed/20008117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00016.2009
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