Tumor necrosis factor-α causes release of cytosolic interleukin-18 from human neutrophils

Neutrophils (PMNs) are a vital part of host defense and are the principal leukocyte in innate immunity. Interleukin (IL)-18 is a proinflammatory cytokine with roles in both innate and adaptive immunity. We hypothesize that PMNs contain preformed IL-18, which is released in response to specific infla...

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Main Authors: Silliman, Christopher C., Kelher, Marguerite R., Gamboni-Robertson, Fabia, Hamiel, Christine, England, Kelly M., Dinarello, Charles A., Wyman, Travis H., Khan, Samina Y., McLaughlin, Nathan J. D., Bercovitz, Rachel S., Banerjee, Anirban
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2010
Fag:
Protein and Vesicle Trafficking, Cytoskeleton
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838563/
https://ncbi.nlm.nih.gov/pubmed/19907017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00011.2009
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