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Construction and Properties of a Herpes Simplex Virus 2 dl5-29 Vaccine Candidate Strain Encoding an HSV-1 Virion Host Shutoff Protein
The replication-defective herpes simplex virus 2 (HSV-2) dl5-29 mutant virus strain with deletions in the U(L)5 and U(L)29 genes has been shown to protect mice and guinea pigs against challenge with wild type (wt) HSV-2 and to protect against ocular disease caused by HSV-1 infection. The dl5-29 stra...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837780/ https://ncbi.nlm.nih.gov/pubmed/20117270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.01.030 |
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