Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers

BACKGROUND: Altered DNA repair may be associated with aggressive tumour biology and impact upon response to chemotherapy and radiotherapy. We investigated whether expression of human AP endonuclease (APE1), a key multifunctional protein involved in DNA BER, would impact on clinicopathological outcom...

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Main Authors: Al-Attar, A, Gossage, L, Fareed, K R, Shehata, M, Mohammed, M, Zaitoun, A M, Soomro, I, Lobo, D N, Abbotts, R, Chan, S, Madhusudan, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837561/
https://ncbi.nlm.nih.gov/pubmed/20087352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605541
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