Membrane association of mitochondrial DNA facilitates base excision repair in mammalian mitochondria

Mitochondrial DNA encodes a set of 13 polypeptides and is subjected to constant oxidative stress due to ROS production within the organelle. It has been shown that DNA repair in the mitochondrion proceeds through both short- and long-patch base excision repair (BER). In the present article, we have...

Full description

Saved in:
Bibliographic Details
Main Authors: Boesch, Pierre, Ibrahim, Noha, Dietrich, André, Lightowlers, Robert N.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836570/
https://ncbi.nlm.nih.gov/pubmed/20007607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1143
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items