Formins regulate the Arp2/3-independent polarization of the MTOC to the Immunological Synapse

T cell receptor (TCR)-mediated cytoskeletal reorganization is considered to be Arp2/3-dependent. We therefore examined Arp2/3- and formin-dependent cytoskeletal processes during T cell activation. We demonstrate that without Arp2/3-mediated actin nucleation, stimulated T cells cannot form an F-actin...

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Bibliografiska uppgifter
Huvudupphovsmän: Gomez, Timothy S., Kumar, Karan, Medeiros, Ricardo B., Shimizu, Yoji, Leibson, Paul J., Billadeau, Daniel D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836258/
https://ncbi.nlm.nih.gov/pubmed/17306570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.01.008
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