Formins regulate the Arp2/3-independent polarization of the MTOC to the Immunological Synapse

T cell receptor (TCR)-mediated cytoskeletal reorganization is considered to be Arp2/3-dependent. We therefore examined Arp2/3- and formin-dependent cytoskeletal processes during T cell activation. We demonstrate that without Arp2/3-mediated actin nucleation, stimulated T cells cannot form an F-actin...

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Hlavní autoři: Gomez, Timothy S., Kumar, Karan, Medeiros, Ricardo B., Shimizu, Yoji, Leibson, Paul J., Billadeau, Daniel D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836258/
https://ncbi.nlm.nih.gov/pubmed/17306570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.01.008
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